Exir Bio
Exir Bio’s goal is to accelerate drug discovery, efficacy, and safety assessments by combining nonhuman primate (NHP) in vitro / in vivo models,
replacing, reducing, and refining (3R’s) the use of NHPs – necessary due to the global shortage of NHPs and in accordance with US Modernization Act
2.0.
Exir Bio has access to ~20,000 NHP’s / 8 species across several colonies in the US, all with known origin and bred in captivity per FDA and European
Union requirements.
MEPSGEN
MEPSGEN delivers an automated MPS ecosystem designed to bridge the gap between in vitro assays and human clinical outcomes. Combining modular MEPS-X chips with the ProMEPS™ automated tissue-culture platform, MEPSGEN enables standardized, reproducible human tissue models for robust efficacy and toxicity assessment, supporting more predictive and decision-ready preclinical research.
Xellar Biosystems
Our platform combines our unique Organ-on-a-Chip technology, multicellular 3D disease model development, and Artificial Intelligence (AI) to provide spatiotemporal profiling and analysis of drug testing and treatment at a cellular level.
Ncardia
For more than a decade, Ncardia has been pioneering innovations in human induced pluripotent stem cells (iPSC).
BiomimX
BiomimX develops the next generation of beating organs-on-chips. uBeat® Platforms and connected hardware provide 3D miniaturized constructs with a tunable mechanical stimulation to model human organs’ function and diseases. uBeat® products and customized drug screening services are available.
AlveoliX
AlveoliX has developed an adaptable organ-on-chip platform that enables the modelling of all tissue barriers, including the associated mechanical forces. Our technology is suitable for a wide range of applications including drug safety and efficacy testing, inhalation toxicology assessment and answering fundamental research questions. Our technology can be implemented in your laboratory, or utilised through our CRO services
ImmuONE
ImmuONE is a product provider of immune cell models and a specialized service provider for chemical safety assessment (e.g. e-cigarettes, cosmetics, therapeutics). We offer advanced in-vitro products and offer innovative in-house testing services using state-of-the-art equipment and techniques.
Emulate
Emulate develops a breadth of Organ-Chip models with a focus on recreating the microenvironment and mechanical forces cells experience in vivo. Hardware automating media flow and stretch, Bio-Kits including chips and qualified human cells, and a range of standard and custom services are available.
SynVivo, Inc.
Organ-on-Chip models from SynVivo recreate complex microvasculature including scale, morphology, hemodynamic shear stress, and cellular interactions in a perfused microfluidic chip environment. Validated models include Air Liquid Interface for Lung, Blood-Brain Barrier, Tumor, DIVI, Inflammation.