Update on Complement-AIRE program & ORIVA – Margaret O. 20 min

NAMs VQN and the first set of pilot projects and the targeted plans for the launch of Implementation of the VQN later this year – Amber Zimmerman – 20 min

Enhancing Regulatory Protocol Quality through an Ethically Governed, AI-ASsisted Review Framework – Jeremy DeRicco, U. of Pittsburg – 15 min

Replacing the second species – Sally Thompson-Iritani, U of Washington – 20 min

Use of learning machines in drug discovery to fight lung diseases – Deepak Deshpande & Raymond Penn, Jefferson – 20 min

Prompting for AI – Szczepan Baran, BaranCafe – 20 min

Stem Cell-based Primate In Vitro Models to Enhance Translational Relevance of Drug Safety – Morteza Roodgar, Exir Bio 40 min

Replacing Non-Human-Relevant Animal Studies with Liver Spheroids: A Case Study in Amcenestrant-Induced Hepatotoxicity – Piyush Bajaj, Lilly – 20 min

Replacing sentinel animals for 3Rs and operational benefits – 15 min – Alicia Donnelly, Children’s Hospital of Philadelphia

Considerations of non-human primate use in nonclinical toxicity study package for oncology therapeutics with well-characterized target in support of 3Rs – an IQ DruSafe industry survey. – Timothy Hart, GSK, 30 min

Precision cut lung slice cultures for Reduction in toxicology – Julia Herbert, Rutgers, 15 min

Enormous Reduction effect through genetic STR analysis of chimeric sperm – Ronald Naumann, Max Plank Institute of Molecular Cell Biology, 15 min (Virtual)

Non-invasive home cage monitoring of body temperature and activity for the evaluation of novel mouse enrichment nesting materials – Vic Johnson, BRT Labs, 20 min

Surgical refinements for laboratory animals – Kristen Gardner, University of Pennsylvania, 20 min

Using positive reinforcement for refinement and cost savings in pigs – Emma Halter, University of Pennsylvania, 20 min