Potentiating NaV1.1 in Dravet syndrome patient iPSC-derived GABAergic neurons increases neuronal firing frequency and decreases network synchrony
Modeling neurodegenerative diseases using in vitro compartmentalized microfluidic devices
Bioprinting Laboratories
Bioprinting Labs’ pillar/perfusion plates enable robust and reproducible organoid culture and in situ analysis. Our products streamline organoid-based assays by facilitating miniature organoid culture and enhancing organoid maturity through dynamic culture in the pillar/perfusion plates.
AIM Biotech
AIM Biotech is a leading bioengineering company, offering scalable, cost-effective 3D cell culture platforms, drug screening services, and customized assay development. By combining model realism and platform simplicity, AIM’s plug-and-play technologies empower drug developers to mimic human biology with precision, delivering clinically-relevant data.
Axol BioScience
Axol Bioscience are leaders in human iPSC products and services for CNS, PNS and cardiac research. Under ISO9001, we manufacture functional hiPSC-derived cells with multi-platform utility for MPS technology, alongside a “one-stop shop” of iPSC lines, services and custom assays.
Exir Bio
Exir Bio’s goal is to accelerate drug discovery, efficacy, and safety assessments by combining nonhuman primate (NHP) in vitro / in vivo models,
replacing, reducing, and refining (3R’s) the use of NHPs – necessary due to the global shortage of NHPs and in accordance with US Modernization Act
2.0.
Exir Bio has access to ~20,000 NHP’s / 8 species across several colonies in the US, all with known origin and bred in captivity per FDA and European
Union requirements.
Antidepressant paroxetine exerts developmental neurotoxicity in an iPSC-derived 3D human brain model
Ncardia
For more than a decade, Ncardia has been pioneering innovations in human induced pluripotent stem cells (iPSC).
Emulate
Emulate develops a breadth of Organ-Chip models with a focus on recreating the microenvironment and mechanical forces cells experience in vivo. Hardware automating media flow and stretch, Bio-Kits including chips and qualified human cells, and a range of standard and custom services are available.