Microphysiological Systems Publication Hub

Microphysiological Systems (MPS) are in vitro models composed of cells, tissue explants, or stem-cell derived ‘organoid’ formations of human or animal origin. These models provide translational biochemical, electrical, and/or physiomechanical responses to represent organ and tissue function, with great potential to replace some animals used in research.

Below you can explore publications from Microphysiological System Companies offering commercially available advanced in vitro models. This page was first published in May 2025, and will be continuously updated.

To learn more about a particular organ system or disease area, you can filter publications by the filters below.  

Article Type

Article Type
  • Original Research (312)
  • Review Article (15)
  • Commentary/Perspective (5)

Tissue/Organ Type

Tissue/Organ Type
  • Tumor (52)
  • Liver (47)
  • Lung (34)
  • Gut (32)
  • Vasculature (32)
  • CNS & Neuro (30)
  • Multi-Organ (18)
  • Skin (17)
  • Heart (12)
  • Kidney (11)
  • Pancreas (10)
  • Reproductive (9)
  • Blood-Brain Barrier (8)
  • Fat (7)
  • Bone (6)
  • Bone Marrow (6)
  • Ocular (6)
  • Lymphatic System (4)
  • Skeletal Muscle (4)
  • Bladder (2)
  • Esophagus (2)
  • Thyroid (2)
  • Cartilage (1)
  • Spleen (1)

Disease Area

Disease Area
  • Cancer (55)
  • ImmunoOncology (23)
  • Inflammation (23)
  • Cardiovascular Disease (18)
  • Infectious Disease (14)
  • Neurological Disease (14)
  • Diabetes (7)
  • Microbiome (7)
  • Neuromuscular Disorder (7)
  • Fibrosis (5)
  • Metabolic Disease (5)
  • Retinopathies (5)
  • COVID-19 (4)
  • Osteoarthritis (4)
  • Aging (2)

Application

Application
  • Model Development (143)
  • Toxicology (38)
  • Efficacy Testing (18)
  • ADME/PKPD (16)