Exir Bio
Exir Bio’s goal is to accelerate drug discovery, efficacy, and safety assessments by combining nonhuman primate (NHP) in vitro / in vivo models,
replacing, reducing, and refining (3R’s) the use of NHPs – necessary due to the global shortage of NHPs and in accordance with US Modernization Act
2.0.
Exir Bio has access to ~20,000 NHP’s / 8 species across several colonies in the US, all with known origin and bred in captivity per FDA and European
Union requirements.
STEMCELL Technologies
We are the world-leading provider of reagents and services for generating organoid and stem cell-derived models of healthy and diseased human tissues.
Organ-on-a-chip model of vascularized human bone marrow niches
This publication presents a 3D in vitro model of human bone marrow that contains both the perivascular and endosteal niches, complete with dynamic, perfusable vascular networks to replicate in vivo bone marrow function, including maintenance and differentiation.
NETRI
NETRI is an industrial start-up developing innovative technologies for the pharmaceutical industry. Its patented organs-on-chip technologies allow the creation of standardized and predictive human in vitro models.
React4Life
React4Life provides MIVO® organ-on-chip technology for advanced in vitro testing. Our platform can closely replicate human physiology by hosting 3D human cells or clinically relevant sized tissues under precisely controlled fluid dynamic conditions. Our multi-organ configuration enables simultaneous investigations into drug efficacy and cytotoxic effects, providing a more comprehensive and relevant context.
AlveoliX
AlveoliX is a Swiss-based organ-on-chip company. Our product is comprised of different hardware components and the easy-to-handle organ-on-chip consumable AX12. On the AX12 healthy and diseased biomodels can be created to study drug safety and efficacy and to answer fundamental research questions.
KIYATEC
KIYATEC’s clinically validated, predictive 3D ex vivo assays characterize response to I/O, targeted, and chemo therapies. Data from our proprietary platforms span most solid tumors including ovarian, GBM, breast, & rare. Our services cover all phases of preclinical development thru clinical trials.
Aracari Bio
Aracari’s vascularized micro-organ and tumor models incorporate perfused human vasculature for the physiologic delivery of nutrients, drugs and immune cells to multiple tissue and tumor types. These powerful next-generation tools are advancing discovery in immuno-oncology and drug development.
SynVivo, Inc.
Organ-on-Chip models from SynVivo recreate complex microvasculature including scale, morphology, hemodynamic shear stress, and cellular interactions in a perfused microfluidic chip environment. Validated models include Air Liquid Interface for Lung, Blood-Brain Barrier, Tumor, DIVI, Inflammation.