PredictCan Biotechnologies
“PredictCan Biotechnologies has patented cell education technology that exploits the intrinsic plasticity of cell lines by inducing subject-dependent phenotypic changes to better model cohorts of healthy or pathological individuals with tailored characteristics. The company generates state-of-the-art 3D individual-centric models for early detection of cancers, drug discovery, drug safety, and drug efficacy. Among our models, GenuineSelect-TOX is a platform that accurately detects intrinsic DILI and immune-mediated idiosyncratic DILI (iDILI) during the early and late stages of drug development.
STEMCELL Technologies
We are the world-leading provider of reagents and services for generating organoid and stem cell-derived models of healthy and diseased human tissues.
AnaBios
AnaBios aims to establish the safety and efficacy of novel compounds through its advanced, human-focused translational technologies, including superior quality human tissue samples and functional assays focused, as well as human primary cells through its subsidiary Cell Systems.
React4Life
React4Life provides MIVO® organ-on-chip technology for advanced in vitro testing. Our platform can closely replicate human physiology by hosting 3D human cells or clinically relevant sized tissues under precisely controlled fluid dynamic conditions. Our multi-organ configuration enables simultaneous investigations into drug efficacy and cytotoxic effects, providing a more comprehensive and relevant context.
AlveoliX
AlveoliX is a Swiss-based organ-on-chip company. Our product is comprised of different hardware components and the easy-to-handle organ-on-chip consumable AX12. On the AX12 healthy and diseased biomodels can be created to study drug safety and efficacy and to answer fundamental research questions.
SynVivo, Inc.
Organ-on-Chip models from SynVivo recreate complex microvasculature including scale, morphology, hemodynamic shear stress, and cellular interactions in a perfused microfluidic chip environment. Validated models include Air Liquid Interface for Lung, Blood-Brain Barrier, Tumor, DIVI, Inflammation.
InSphero
InSphero is the pioneer of industrial-grade, 3D-microtissue-based assay solutions and scaffold-free 3D organ-on-a-chip technology. The company specializes in liver toxicology, metabolic diseases (e.g., T1 & T2 diabetes and NAFLD & NASH liver disease), and immuno oncology.
Hesperos Inc.
Hesperos is accelerating drug discovery by providing safety and efficacy testing services using its Human-on-a-Chip, microphysiological system. This breakthrough technology enables unprecedented preclinical insight bringing better therapies to patients faster without the need for animal testing.
Altis Biosystems
Altis Biosystems has developed a stem cell platform that recreates the human intestinal epithelium, using proliferative stem cells and terminally differentiated cells. These cells are sourced from transplant-grade intestine. It is a high-throughput format, ideal for drug screening.